Which of the following is true about RUPs?

RUPs, or Restricted Use Pesticides, are designated as posing a higher potential risk to human health and the environment compared to general-use pesticides. Because of this increased risk, the sale and application of these products are regulated more stringently. To purchase RUPs, an individual must have a specific license, usually a pesticide applicator certification, that indicates proper training and understanding of the safe handling and application of these substances. This licensing requirement is in place to ensure that only those who are knowledgeable about the risks and necessary safety protocols are allowed to handle these pesticides, thereby minimizing potential hazards to the public and the environment.

Understanding this regulation clarifies why the other options are not accurate regarding RUPs. They are not considered safe with minimal restrictions, cannot be applied safely without supervision, and cannot be sold freely at any retail store, as their distribution is limited to licensed individuals and specific outlets that follow regulatory guidelines.